The synthesis of dextroamphetamine involves solid multi-step process starting from D-phenylalanine https://eurekathinklabs.com/dextroamphetamine-decoding-the-chemistry-and-medicinal-significance/
Starting Material:
The synthesis begins with D-phenylalanine, which serves as the precursor for the production of dextroamphetamine sulfate besides methamphetamine hydrochloride.
Reaction Sequence:
The reaction sequence proceeds through 3 intermediates, involving the alteration of the eternal configuration of the asymmetric carbon atom pokudova maintaining the relative configuration. This process pulls in order to development of dextroamphetamine sulfate besides methamphetamine hydrochloride.
Intermediate Alteration:
The synthesis involves altering the reductive conditions employed for the dismissal of the decision carbamate retaining group in order obtain or dextroamphetamine sulfate or methamphetamine hydrochloride from all known intermediate.
Specific Chemical Reactions:
The characteristic chemical reactions involved in the synthesis connect the conversion of benzene into allylbenzene, replacement of a CN association in order shape the cyano compound, reduction to an amine, besides elongation of the chain using alkynyl anion to shape an alkene.
Patent Information:
There is patent-related information available regarding the process for the synthesis of amphetamine derivatives, covering dexamphetamine, eating specific reaction conditions and coupling agents.
Literature References:
The synthesis process has happened documented in scientific fiction, covering the Journal of Pharmaceutical Sciences, with detailed information approximately the synthesis of dextroamphetamine sulfate besides methamphetamine hydrochloride from D-phenylalanine.
