Sixty nine Fisting considerably elevated the risk of HCV infection among HIV-contaminated MSM by more than five-fold (aOR 6.27-12.6), 61, 70 as did the usage of sex toys (78% versus 43%). 61 In addition, the usage of psychoactive substances was widespread among HCV/HIV-coinfected MSM and might need acted as a disinhibitor for dangerous sexual practices, cheap dildos resulting in traumatic sex and anal toys mucosal harm. 55, 74 Thus, some researchers have concluded that the actual risk of sexual transmission in HIV-contaminated individuals outcomes from blood-to-blood contact during sex. It is worth noting that phylogenetic analyses in cohort studies 50, 75 and in an international network of MSM 68 have additionally indicated concordance of gene sequences in recovered HCV strains. 69 Fisting was extremely correlated with use of sex toys, group intercourse, and bleeding in a cross-sectional research from Amsterdam. 69 Participation in group intercourse significantly increased the odds for HCV infection (aOR cheap dildos 9.16, 95% CI 3.51-23.9) if it concerned a minimum of two of the following 4 sexual practices: receptive and insertive anal intercourse and receptive and insertive fisting. The difficult-to-deal with genotypes 1a and cheap dildos 4d have been often recovered. 15-20, 50, 54, 61, 63, 69, 70, 74-78 In the one properly-designed case control study so far, participation in group intercourse was extra prevalent among HIV-coinfected HCV cases in contrast with controls (88% versus 52%).
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